Welcome to Mauvezin Lab
Our research aims to uncover how cancer cells acquire and tolerate genomic instability by dissecting the molecular processes that govern mitosis, autophagy, and chromosome maintenance. Because chromosomal instability is a defining hallmark of tumor progression, understanding how pathways such as replication stress responses, lysosome‑dependent degradation, and autophagy shape cell‑division fidelity allows us to identify the upstream events that destabilize the genome. By integrating these mechanistic insights, our laboratory seeks to reveal new vulnerabilities in cancer cells and pave the way toward more precise CIN‑targeted therapeutic strategies.
Our laboratory in the Department of Biomedicine at the University of Barcelona stands at the interface of two prominent fields in cancer research, autophagy and cell division.
Our Research
Collaborations
We collaborate with basic and translational research teams to strengthen both the mechanistic depth and clinical relevance of our work. These partnerships enhance our ability to uncover the drivers of chromosomal instability and accelerate the transfer of fundamental discoveries into therapeutic strategies. We are actively open to new collaborations that broaden our scientific reach and impact.
Our research is supported by competitive national and international funding agencies, whose contributions enable us to pursue innovative projects in genome stability and cancer biology. Their commitment not only sustains our ongoing work but also reinforces the essential role of fundamental research, where early discoveries lay the groundwork for future therapeutic advances. We are deeply grateful for this support and remain open to new funding opportunities that strengthen our mission and expand the impact of our science.
Join Our Insights
Stay updated on toroidal nucleus research
